tirzepatide results reddit 10 week progress pics and overall update. : r/tirzepatidecompound Using AI to surface unreported

My Approach When Prescribing Here's my general framework not a rigid protocol, but a starting point for the conversation: I Tend to Start with Semaglutide When The patient has established cardiovascular disease (because of the SELECT trial data) Insurance covers semaglutide but not tirzepatide The patient has MASH/fatty liver disease Cost is the primary concern and semaglutide is more accessible I Tend to Start with Tirzepatide When Maximum weight loss is the primary goal The patient has type 2 diabetes (tirzepatide shows greater A1C reduction roughly 2.02.5% vs 1.02.0% for semaglutide) The patient has tried semaglutide with insufficient results Insurance covers both options equally Regardless of which medication we choose, I always emphasize that GLP-1 therapy is most effective when combined with nutritional counseling, physical activity, and behavioral support

Chronic stress leads to cortisol-mediated increase in quantity as well as higher carbohydrates and fat consumption

Patients with depression exhibit impaired neuronal activity and disrupted synaptic plasticity, leading to structural alterations in brain regions involved in emotion and stress regulation, such as the hippocampus and prefrontal cortex

Hunger, cravings, metabolism, blood sugar regulationits hitting all of those levers simultaneously rather than just one or two