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Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity

It improves insulin sensitivity. Glucose and insulin measurements changed in diet-induced obese mice

If you have been on long term medication like omeprazole or lansoprazole, have had a poor diet or are vegan/vegetarian you may benefit from having a course of Vitamin B12 Injections

The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)