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Additionally, [6]-shogaol and hydroxy -sanshool were found to be associated with an increase in ADM (adenylate cyclase-activating polypeptide) production

Pre-clinical and cosmetic-research data describe increased collagen and elastin synthesis, fibroblast proliferation, improved barrier-protein expression, and reduced markers of oxidative stress following GHK-Cu exposure

So you're talking an accounting error for big pharma