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Sarah is 38 years old, 5 feet 5 inches, and weighs 198 pounds

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Cytokines, such as tumour necrosis factor-alpha (TNF-), interleukins (ILs) and transforming growth factor-beta (TGF-), play central roles in promoting inflammation and fibrosis.7 10 Additionally, extracellular vesicles (EVs), which are released by damaged hepatocytes and other liver cells, carry signalling molecules like microRNAs (miRNAs) and proteins that modulate immune responses, fibroblast activation and lipid metabolism.11 These EVs act as critical mediators of intercellular communication, spreading inflammatory and fibrogenic signals both locally within the liver and systemically, contributing to extrahepatic complications of ALD

7A, biomineralized GOx-Mn/HA were synthesized through coordination-driven self-assembly between GOx and manganese ions, followed by surface functionalized with HA via electrostatic adsorption