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A literature review and meta-analysis of safety profiles of SGLT2 inhibitors in Japanese patients with diabetes mellitus

If approved for the treatment of obesity, orforglipron could provide a convenient alternative for the millions of individuals living with obesity around the globe to continue their long-term health journey." In the study, orforglipron met the primary endpoint of superior percent maintenance of body weight reduction compared to placebo, among SURMOUNT-5 participants who previously reached a body weight plateau

doi: 10.1172/JCI10842 114 da SilvaAAdo CarmoJMLiXWangZMoutonAJHallJE

All CKD patients with a first episode of gout should be treated with hypouricemic drugs to achieve baseline UA levels of less than 6 mg/dl ( 55%)