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In: Shiomi N, Waisundara V, editors

GLP-1 receptor agonist medications are FDA-approved for adults who meet one of the following criteria: a body mass index (BMI) of 30 or higher (classified as obesity), or a BMI of 27 or higher (overweight) combined with at least one weight-related health condition such as type 2 diabetes, high blood pressure, high cholesterol, sleep apnea, or cardiovascular disease

However, worth noting, Retatrutide remains a research compound only , it isnt approved for any therapeutic use, and all comparisons refer strictly to pre-clinical research findings