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Smoking a cannabis cigarette showed an increase in the resting measurement of systolic blood pressure times heart rate of 54%, increased the venous carboxyhemoglobin level, and decreased the exercise time until angina by 50% in ten patients with angina pectoris

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In Study 4, patients treated with CHANTIX had a superior rate of CO-confirmed abstinence during weeks 9 through 12 (44%) compared to patients treated with bupropion SR (30%) or placebo (17%)

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