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Cannot increase to a higher dose Sometimes, people do not feel as much appetite reduction with semaglutide because they are not able to increase to a higher dose, or they may not tolerate higher doses due to side effects like nausea or stomach upset, says Karalis, RD

Whether youre using Wegovy, compounded injectables, or another GLP-1 formulation, the focus shifts from increasing to sustaining. Your provider may reassess your dose every 8 to 12 weeks depending on progress

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Thats why continuing healthy habits, or sometimes staying on the lowest effective dose of medication, makes long-term success more likely