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There are some very rare side effects listed in medical literature (mostly when large doses are given): for example, one out of many thousands of patients might develop a disturbance in liver enzymes or a tingling in the fingers or toes

Cochrane Database Syst Rev 2011:CD008716 Zhao LN, Yu T, Lan SY, Hou JT, Zhang ZZ, Wang SS, Liu FB

Before approving a new drug, the FDA typically requires companies to conduct a type of study called a randomized controlled trial, in which study participants are allocated by chance to groups that either receive the drug, or are administered a placebo

Step 2: Determine Your Dosage Most people find success with 1 to 2 tablespoons (1530 mL) of apple cider vinegar per day