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The twist at the mouth end acts like a built-in stopper, which is pretty clever

The G allele of a second variant in the region, rs7096169 (intronic to BORCS7 and only in weak LD with rs12780116, r 2 = 0.18 in 1000G Europeans) increases smoking initiation and reduces expression of BORCS7 and AS3MT in eight brain tissues (including dorsolateral prefrontal cortex in the Brain xQTL and was the top BORCS7 eSNP in GTEx in the Cerebellar Hemisphere, Cerebellum, and Spinal cord cervical-C1)

Likewise, support was strong regardless of educational background 74% of those who didnt finish high school endorsed the change, as did 75% of high school graduates, 74% of those who finished some college and 76% of those with a college degree

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