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Through appropriate patient selection, personalised meal planning with micronutrient adequacy, careful management of the ketosis transition, close monitoring, and ongoing education, such multidisciplinary care may help minimise adverse effects, support adherence, and optimise clinical outcomes [67]

Synovitis, inflammation of the synovium, can occur in the early stages of OA 7,8

Individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN2) are typically excluded from retatrutide trials

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