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There are diagnostic difficulties in this set of patientsthe simplified score may classify a significant proportion of these patients as probable (5083%) [5, 169,170,171,172,173], IgG may be normal in up to 53% [167,168,169,170,171,172,173], and 043% of these patients are seronegative [5, 167,168,169,170,171,172,173]

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Genetic Predispositions and Metabolic Readiness for GLP-1 Therapy Individual response to GLP-1 therapy varies significantly based on genetic variants in appetite regulation and glucose metabolism pathways