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[8] Melanotan II produces melanogenesis by activation of the MC 1 receptor, whereas its clinically documented sexual effects are thought to be related to its ability to activate the MC 4 receptor (though the MC 3 is thought to also possibly be involved)

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Peroxiredoxin (Prx) 3, a cysteine-dependent peroxidase enzyme, is also present in the mitochondria, whereas Prx5 can also be found in the cytosol, in peroxisomes, and in the nucleus [28]