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In contrast, in the group treated with TPA alone, the mitochondrial membrane became denser, the mitochondrial cristae were incomplete, the cristae were fractured, and the mitochondrial matrix became darker in colour

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Whereas non-cystic fibrosis cells upregulate CHAC1 following infection with various pathogens (including Pseudomonas aeruginosa , human coronavirus, cytomegalovirus, tick-borne flaviviruses, Zika virus, and Mycoplasma hominis ), cystic fibrosis cells show an impaired response