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Further oxidation of Hz and AcHz by CYP450 enzymes, particularly CYP2E1, generates reactive intermediates that form covalent adducts with endogenous macromolecules, a process implicated in INH-induced hepatotoxicity (Delaney and Timbrell, 1995
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Pour comprendre les facteurs personnels qui peuvent contribuer au gain de poids, des chercheurs de la Penn State University ont analys les donnes de plus de douze mille participants volontaires la cohorte National Health and Nutrition Examination Survey (NHANES)
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