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Ignoring the Fundamentals: We've said it before, but it bears repeating

A review of studies of melatonin in tinnitus treatment concluded that it could have a positive effect on sleep problems caused by tinnitus

Together, these two mechanisms explain why low-dose atropine can paradoxically enhance vagal effects and slow sinoatrial node firing before higher doses shift the balance toward the expected anticholinergic tachycardia

Also shown are the adverse clinical outcomes associated with elevated systemic TMAO levels in subjects, and enhanced cardiometabolic phenotypes observed with elevated TMAO levels in animal models (46, 12, 13, 1618)