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GLP-1 receptor agonists such as semaglutide established that pharmacologic activation of gut hormone pathways could produce double-digit percentage weight loss in many patients

Similar to the statin lipid-lowering drugs mentioned earlier, other lipid-lowering drugs, such as probucol, also exhibit the capability to restore the inhibited GSH system and defend the myocardium from oxidative damage after exposure to pathological factors, for example, ISO and cyclophosphamide [242, 243]

Response: We note that the two SDOH measures went through the rigorous measure development lifecycle outlined at the CMS Measures Management System website [269] which includes measure testing and reliability analysis