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Interestingly, in the context of Wnt/-catenin signaling-dependent liver tumorigenesis, it was suggested that TCF4 might act in concert with the FOXA factors to regulate hepatocellular carcinoma-specific Wnt target gene expression 73
Coenzyme Q and squalene, two other hydrophobic metabolites, have been implicated to act as novel lipid peroxide scavengers besides GPX4 21,22,23
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