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The clinical concern is not about drug testing but about gastroparesis risk: semaglutide slows gastric emptying, which can increase aspiration risk under general anesthesia if fasting protocols are not appropriately extended

Additionally, the FDA has documented specific safety concerns with compounded injectable semaglutide products, including reports of dosing errors related to dose-unit conversions that have led to overdosing

Certain medications, foods, and supplements can trigger false positive results on immunoassay screens due to structural similarities between harmless compounds and the target substances

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