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Up to 70% of smoker patients with NSCLC express EGFR WT protein [13] and also had shorter progression-free survival (PFS) than those with activating mutations or without smoking history in response to EGFR TKI treatment [10, 14]

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Nicotine and other harmful substances from vaping products can be present in breast milk, potentially affecting infant health and development if the mother vapes while breastfeeding