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He wrote a detailed response to Health Canada, concluding: "Rather than seeking to create a series of ill-advised comparative risk statements, Health Canada is encouraged to take effective action to mitigate serious public health problems associated with e-cigarette use." Tobacco-control advocate Stanton Glantz, a professor of medicine at the University of California, San Francisco, warned Health Canada that the proposed health claims "could be misread by consumers and potential consumers as indicating that e-cigarettes are safe." Fontem Ventures, which markets the Blu vaping device, said in a submission that it "applauds" Health Canada for the initiative

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While these products have generally become safer over the last few decades, it has been known to experts for much longer that their health risks pale in comparison to those of cigarettes

This study reports that acrolein mediates the neurogenic effects of cigarette smoke by stimulating TRPA1 receptors