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Signage, education, and messaging have certainly helped prevent new smokers, and cessation help has been beneficial for helping the smokers in quitting. Koch warned, however, that alternatives to smoking arent nearly as beneficial as quitting altogether

Here we leveraged global genetic diversity across 3.4 million individuals from four major clines of global ancestry (approximately 21% non-European) to power the discovery and fine-mapping of genomic loci associated with tobacco and alcohol use, to inform function of these loci via ancestry-aware transcriptome-wide association studies, and to evaluate the genetic architecture and predictive power of polygenic risk within and across populations

I can hardly walk across a room