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In AMPLITUDE-O possible dose-dependent effect for the MACE occurrence was observed

MIC assay Stationary-phase bacterial cultures were diluted 1:1,000 in MHB containing serially diluted Rif (0200 g ml 1 ), Mox (020 g ml 1 ) or Van (016 g ml 1 ) in 96-well assay plates (Corning) in triplicates (200 l per well)

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