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On a call with investors Wednesday, David Moore, president of Novo Nordisk U.S., said early uptake of the Wegovy pill was more than twice that of any previous weight loss drug launch in the United States

In semaglutide users, they made up 10.6% of minimal responders and 5.8% of high responders

Patients allergic to tirzepatide, with a history of medullary thyroid cancer, MEN 2 syndrome, pregnant and breastfeeding females, and children should not use tirzepatide

Additionally, urinary tract infectionswhich are not directly caused by GLP-1 receptor agonists like Rybelsus but may occur coincidentallycan produce a strong, unpleasant smell and should always be considered when evaluating new urinary symptoms