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Moreover, the association observed in some epidemiological studies could be sustained by the fact that T2DM and TC could share some common risk factors, such as obesity and increasing age (Kitahara et al., 2020), and TC is often diagnosed incidentally in patients with T2DM due to the performance of screening imaging (such as carotid artery ultrasound), potentially leading to a selection bias (Croce et al., 2023)

old cravings subside and the energy increases as the body adapts to consuming fewer calories

Structural model determination Due to intermediate exchange only a few inter-molecular NOEs could be obtained