Rodil, R
Oral doses of 0.55mg are most common in published research, but 4060% first-pass metabolism means actual CNS exposure is significantly lower than nominal dose
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What a targeted study would look like A randomized human clinical trial comparing placebo to CLA alone, L-carnitine alone, and the combination over six to 12 months with body composition by DXA, fasting metabolic markers, kidney function and TMAO measurement would be ideal