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In conclusion, this meta-analysis showed a significant association between low GPx level and vitiligo for Asian population or segmental patients

The individual amino acids are absorbed and can be used to resynthesize glutathione intracellularly, but this is a slow, rate-limited process that does not produce the acute plasma elevation seen with parenteral routes

The reduction in the activity of GPx may predispose the body to accumulate hydrogen peroxide and lipid peroxides, as GPx activity reduces both hydrogen peroxide and lipid peroxides