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Ultimately, the radical chain reactions will be blocked by the antioxidant enzymes superoxide dismutase (SOD) in association with catalase or GPX that determines the complete free radicals scavenging (Winterbourn, 1993)

Intervention studies High-dose B-vitamin supplementation has been proven effective for treating hyperhomocysteinemia in elderly individuals with or without cognitive impairment

The following ten genes were screened using the MCC method in CytoHubba within Cytoscape: SLC7A11, HMOX1, G6PD, AURKA, RRM2, KIF20A, HELLS, STEAP3, GPT2, and GLS2 (Fig