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Weight-bearing exercise invokes Wolff's Law, the principle that bone responds to mechanical stress by becoming denser and stronger

The genetic information for the several enzymes and transporters involved is packed into a long strand of bacterial DNA (a gene cassette ), which in turn can be transmitted as a whole from one microbial cell to others through a genetic mechanism known as horizontal gene transfer, thus spreading antibiotic resistance throughout the pool of environmental micro-organisms

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doi: 10.1080/14728222.2018.1439016 103 LuoJAttardGBalkSPBevanCBurnsteinKCatoLet al