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As shown in the Table above, polymorphisms exist in the ADH1B and ADH1C genes, and the different enzymes that result from these polymorphisms are associated with varying levels of activity

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Side effects usually come from low-quality probiotics or due to one of the following reasons: Low-quality probiotics with unstudied bacterial species and strains Using cheap probiotics that contain fillers or binders Taking your probiotic on an empty stomach A negative reaction to prebiotics that has been included in the probiotic formulation (prebiotics act as food for the bacteria in your gut) Consuming probiotics that have not been temperature-controlled or climate-controlled (certain bacterial species MUST be refrigerated or they will die) Very few people have true negative reactions to probiotics