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In line with these results, matrix Grx1roGFP2 responses in a tsa1 tsa2 strain became attenuated upon application of exogenous H 2 O 2 at lower concentrations than those used in assays with the wildtype strain (Appendix Fig S4C)

The drugmaker which was known as Mallinckrodt Pharmaceuticals before merging with Endo and rebranding as Keenova last year said that Xiaflex (collagenase clostridium histolyticum) met its objectives in a phase 3 trial in plantar fibromatosis patients and will be filed for approval in the new indication before the end of the year

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