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Therefore, reducing intracellular GSH levels has emerged as a promising strategy to overcome therapeutic resistance and improve treatment efficacy [18]

33 Non-specific cysteine transporters While influx transporters are the main means by which cells acquire cystine, cysteine can also be taken up from the extracellular milieu into cells directly by excitatory amino acid transporter 3 (EAAT3) and the alanine-serine cysteine transporters 1 and 2 (ASCT1/2), all of which are known to be overexpressed in different cancer types 34 (Table 1)

This study employed BSA as the receptor in the interaction analysis with the amlodipine molecule

It serves two protective functions