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Front Cell Dev Biol (2020) 8619888:619888

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The 0.25 mg dose is typically used as an initial dose to help the body adjust to the medication, whilst 0.5 mg, 1 mg, and 2 mg are maintenance doses used for ongoing blood glucose control

secondly, it protects the stability of red blood cell membranes, preventing hemoglobin from being oxidized to methemoglobin, which loses its oxygen-carrying capacity