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Summary: GLP-1 receptor agonists may reduce alcohol consumption in some individuals, but they are not approved for treating alcohol use disorder and evidence remains preliminary

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According to FDA prescribing information, these include: Nausea (occurring in 1544% of patients depending on formulation and dose) Vomiting (524% of patients) Diarrhea (830% of patients) Abdominal pain (511% of patients) Constipation (324% of patients) These gastrointestinal symptoms typically emerge during dose escalation and often diminish over time as physiological tolerance develops