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The NAC and placebo arms were stratified according to clinical parameters listed in Table 1A, and did not differ between groups, except for maternal pre-gravid BMI, which was slightly higher in the NAC arm in severe IPTB cases (Supplementary Table S2)
Furthermore, in ACLF, sepsis is an important precipitating factor for decompensating liver failure and HE in previously stable patients with cirrhosis [54], indicating the importance of inflammation in the pathogenesis of the disease
They fit into modern routines easily
Prevention has often been lauded as the holy grail of pharmacologic treatment, with the power to curb rising healthcare costs and mortality rates
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