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a) Nitrosative and oxidative stresses assay in the hippocampus Biomarkers of oxidative stress were assay in hippocampi homogenates using established and previously described protocols: malondialdehyde (MDA) with thiobarbituric acid [25] [26] , reduced glutathione (GSH) with 2,2-dithio-5,5-dinitrobenzoic acid [27] , superoxide dismutase (SOD) with adrenaline [28] , catalase (CAT) with Hydrogen peroxide [29] and nitrite with griess reagent [30] [31] , respectively

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Serum and tissue samples from the human gastrointestinal have dysregulated ROS levels ( H