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Its the last of the nations major tobacco companies to market an electronic cigarette in an industrywide push to diversify beyond the traditional cigarette business, which has become tougher in the face of tax hikes, smoking bans, health concerns and social stigma

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The WHO and CDC define heavy smoking as 20 or more cigarettes per day which equals exactly one pack per day

Analytical grade chemicals nitrone spin trap phenyl- N - tert -butylnitrone (PBN), tert -butylbenzene, (2,2,6,6-tetramethyl-piperidin-1-yl)oxyl (TEMPO), and 1- 1-oxidanyl-2,2,6,6-tetramethyl-piperidin-4-ol (TEMPOL) were obtained from Sigma-Aldrich (St