The rising appeal of GLP-1 drugs for cosmetic weight loss has led to a significant increase in off-label prescribing, which can result in unnecessary claims, legal or ethical dilemmas and the risk of poor health outcomes for individuals who may not receive the right support for their condition
However, you should get medications containing metformin from an in-person provider if you have liver or kidney disease, heart failure, low blood pressure, alcohol dependence, or a history of lactic acidosis
The difference is not about one being better than the other, but about their distinct roles in a skincare approach
Tesamorelin has a more established evidence base, primarily in the context of HIV-associated lipodystrophy, where pivotal randomised controlled trials (including Falutz et al., NEJM, 2010) demonstrated statistically significant reductions in visceral adipose tissue