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Although reactive electrophiles such as chloroacetamides are generally considered to be promiscuous in target binding, we demonstrated here using a BODIPY-labelled analogue that the chloroacetamide-based GSTO1 inhibitor C1-27 exhibited a low degree of nonspecific reactivity

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doi: 10.1016/j.biopha.2023.114465 28 SakashitaMTanakaTInagiR

2021 The CHMP of the European Medicines Agency recommends marketing authorization for Wegovy(Semaglutide brand name) Jan.2022 Wegovy is approved for medical use in the European Unioin Jan 2023 The label for Semaglutide oral version Rybelsus is updated to reflect its use as a first-line treatment for adults with type 2 diabetes