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Colorectal Dis 2003;5(4):347352

When receptor proteins on limbic system nerve cells are exposed to high levels of dopamine neurotransmitter molecules for prolonged periods of time, the nerve cells turn down the volume of the signal by lowering the number of receptor proteins on their surfaces

As a result, the Commission issued quarantine orders of licensed vaporizer products, and focused investigative activity into vitamin E acetate (VEA), which the CDC identified as a chemical of concern found in vaping products used by people with associated lung injuries or EVALI