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FUTURE LANDSCAPE OF OBESITY PHARMACOTHERAPY In addition to the published STEP trials, the programme includes three further ongoing global phase IIIa studies in adolescents with obesity (STEP TEENS), 69 in individuals with heart failure and obesity (STEPHFpEF) 70 and in individuals with heart failure and obesity with type 2 diabetes (STEPHFpEFDM) 71 (Figure 2)

This decrease highlights the critical importance of monitoring and comprehending trends in reproductive health and the necessity for targeted interventions to promote mothers and infants well-being

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