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NADPH generation is critical to host antioxidant defense via glutathione reduction ( Figure 1A-2 ), and is also essential for anabolic cellular metabolism, including synthesis of nucleotides, fatty acids, and amino acids ( Figure 1A-3 )

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Free radical scavengers vitamins A, C and E plus magnesium reduce noise trauma

Saunders and Levitt 128 provided elegant demonstration that the fentanyl-induced changes in Te and Ti occurred in parallel in the in situ arterially-perfused rat brainstem preparation