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In a 12-week, randomized, placebo-controlled trial in which 50,000 IUs (1,250 mcg) vitamin D was given weekly to 30 overweight women (age 1849) with PCOS and vitamin D deficiency, supplementation led to reduced unwanted hair growth and male hormone levels

Interestingly, 78c showed no activity against ADP-ribosyl cyclase at concentrations up to 50 nM, while it exhibited no modulatory effects on CD157, suggesting its specificity toward CD38 139

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A deficiency in vitamin B12 can lead to an increase in melanocyte skin cells, which may boost melanin production