C th khng nh Glutathione dng kh c cng dng mnh hn, kh nng o thi c t cho c th, kh nng chng li cc gc t do v kh nng h tr lm trng da vt tri hn so vi Glutathione
Abbreviations ATC: anaplastic thyroid carcinoma AP: apurinic/apyrimidinic or abasic APE1: apurinic/apyrimidinic endonuclease 1 BER: base excision repair GSH: glutathione TME: tumor micro-environment AP probe-net: AP sites capture reagent WB: western blotting RIT: radioiodine therapy DNS: 2,4-dinitrobenzene sulfonamides MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide RMPI 1640: Roswell park memorial institute 1640 FBS: fetal bovine serum DMSO: dimethyl sulfoxide TBST: tris-buffered saline Tween GSS: glutathione enzyme DSBs: double-strand breaks NSCLC: non-small cell lung cancer References Lorimer C, Cheng L, Chandler R, Garcez K, Gill V, Graham K, et al
However, very high doses unlikely providing proportionally greater benefits due to receptor saturation
After centrifugation at 15,000 g for 50 min, the cell supernatant was incubated with GST beads (Cytiva, Glutathione Sepharose 4B, 17075605) at 4 C for 1.52 h