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Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

Bitter Orange Extract Bitter orange extract is found in some citrus fruits and contains synephrine, a stimulant with effects similar to ephedrine (a dangerous ingredient banned by the FDA for use in diet and sports supplements because it showed to have serious health risks like heart attack and stroke, resulting in deaths), according to a 2022 review of the safety and efficacy of bitter orange extract in Nutrients

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Years of antibiotic use or other medications can impact your microbiome