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Several factors increase the likelihood of developing Graves disease: Gender and Age: Women are 7-8 times more likely to develop the condition, particularly between ages 30-50 Family History: People with relatives who have Graves disease face a higher risk Other Autoimmune Disorders: Conditions like type 1 diabetes or rheumatoid arthritis increase susceptibility Smoking: Cigarette smoking significantly raises the risk and can worsen eye problems Pregnancy: Pregnancy or recent childbirth can trigger the onset Emotional Stress: Severe emotional or physical stress may contribute to development Environmental Factors: Exposure to certain viruses or bacteria might trigger the condition Complications of Graves disease The most significant complications include: Heart Problems: The condition can cause irregular heartbeat (arrhythmia), increasing the risk of stroke and heart failure