The copper uglies typically appear within 1 to 3 weeks of starting copper peptides and show up as redness, small bumps, sensitivity, or breakout-like reactions
Falcon CR, Cattaneo M, Panzeri D, Martinelli I, and Mannucci PM (1994)

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the discrepancy between the amelioration in the perceived penile erectile function at IIEF-6 questionnaire and the lack of significant changes in the penile vascular function at dynamic PDU in patients with severe vasculogenic ED might be explained by a potential psychological benefit deriving from treatment, mainly represented by a significant improvement of the subjective perceived quality of penile erection, which was not reflected by an objective improvement of the severe underlying organic disease, a discrepancy occasionally reported in the clinical practice