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The exact causes of gastroparesis remain unclear, but approximately one-third of reported cases are linked to uncontrolled diabetes, according to the Cleveland Clinic

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Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience: Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions

Joshua Silva, MD Nov 19, 2025 5 min read If youre comparing Zepbound (tirzepatide, GLP-1/GIP) vs