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The results are that -cell function was improved, and fasting glucagon levels were reduced in patients treated with TZP, better than dulaglutide, improving several markers of pancreatic -cell function, as exposed by dose-dependently decreasing proinsulin levels, proinsulin/insulin ratios and proinsulin/C-peptide ratios and increasing HOMA2-B indices

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Notably, no signal for ION was detected with tirzepatide, a dual GLP-1/GIP receptor agonist used for diabetes and obesity, and comparator drugs such as metformin and insulin also showed no significant associations

Seeds that did not germinate or develop were not taken into consideration when calculating the average root length or biomass