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Our findings illustrate that liraglutide activates GLP-1Rexpressing neurons in the dorsal LS (dLS) (Figure 1), and knockdown of GLP-1Rs in the dLS, but not the Arc or PVN, diminishes liraglutides weight-reduction effects (Figure 2)

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In summary, the effect of cannabis administration on the following endocrine markers was assessed: total ghrelin, acyl-ghrelin, leptin, GLP-1, and insulin